Guillaume VOGIN, MD, PhD

Business address:

Institut de Cancérologie de Lorraine UMR 7365 CNRS-Université de Lorraine, IMoPA
Department of radiation oncology Biopôle de l’Université de Lorraine, Campus Biologie-Santé,
6, avenue de Bourgogne 9, Avenue de la forêt de Haye, CS 50184,
54511 – Vandœuvre-lès-Nancy Cedex, FRANCE 54505 Vandœuvre-lès-Nancy, FRANCE

Phone : +33-3. 83. 59. 84. 27

Fax : +33-3. 83. 59. 83. 91

E-mail :

Current position: Associate Professor – Senior radiation oncologist – Nancy Medical School, Université de Lorraine

Fields of expertise: sarcomas, CNS malignancies, pediatrics, SBRT, proton- and carbon ion beam radiation, unusual toxicities of radiotherapy

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 Main research field: 60% of adults and 80% of children survive their cancer; Of the 175,000 patients treated with radiotherapy each year in France, 10-15% are confronted with an “unusual” and unpredictable toxicity profile that can lead to sequelae. In pediatrics in particular, the cumulative incidence of sequelae at ≥30 years after primary treatment reaches 73.4% and is increasing. The emphasis is now on the quality of survival and the detection of the most radiosensitive individuals – making it possible to personalize the radiotherapy protocols to individual radiosensitivity.

In this perspective, I develop projects with the team 1 of the UMR 7365 CNRS-UL (Isabelle BEHM-ANSMANT and Christiane BRANLANT) to decipher biological mechanisms of this radiosensitivity at the molecular level. New biomarkers are being investigated by studying the alternative splicing of pre-mRNAs and the expression of non-coding RNAs in the cells of patients who have experienced unusual side effects after radiotherapy. We collaborate closely with the ICL-basic research laboratory CNRS 7039 CRAN, the IBISA National Platform for Cellular and Tissue Optical Imaging, the Genomics Platform of the Luxembourg Institute of Health and the INSERM Unit 866 (Dijon).

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Miscellaneous: Candidate astronaut, European Space Agency 2008 selection

Le 1/06/2017